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Thursday, 30 August 2018 14:19

UFS: Post Doctoral Research Fellowship 2019

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UFS entrance CUFS logo c

 POST DOCTORAL RESEARCH FELLOWSHIP AT THE UNIVERSITY OF THE FREE STATE

UCT 150NHLS

PROFESSOR/ASSOCIATE PROFESSOR & HEAD OF DIVISION: MEDICAL MICROBIOLOGY

DEPARTMENT OF PATHOLOGY

UNIVERSITY OF CAPE TOWN FACULTY OF HEALTH SCIENCES THE NATIONAL HEALTH LABORATORY SERVICE (NHLS)

WITS

UNIVERSITY OF THE WITWATERSRAND, JOHANNESBURG

FACULTY OF SCIENCE

SCHOOL OF MOLECULAR & CELL BIOLOGY

SENIOR LECTURER/ASSOCIATE PROFESSOR IN MICROBIOLOGY

Wednesday, 04 July 2018 11:25

Post Doctoral Research Fellowship

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IMBM lab

Institute for Microbial Biotechnology and Metagenomics, University of the Western Cape, South Africa

Wednesday, 04 July 2018 10:21

SARChI PhD Position

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IMBM 150                UWC 150           Univ Cape Town 150          Structural Biology Research Unit 150

 

Structural elucidation of a novel OlsB protein

 

Ornithine acyl-ACP N-acyltransferase (OlsB) is the protein that is required for the first step of ornithine lipid (OL) biosynthesis.  In this step ornithine is N-acylated with a 3-hydroxy-fatty acyl residue in order to obtain lyso-ornithine lipid (LOL).  Both OL and LOL are biosurfactants, and recently the IMBM patented the use of a novel OlsB to heterologously produce these in Escherichia coli and Pseudomonas putida. These biosurfactants have valuable application in a number of products suitable for waste water treatment, agriculture and cosmetics. The aim of the PhD study is to elucidate the structure of this particular OlsB protein and examine the possibility of manipulating the properties of the protein for various commercial applications.

 

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