Displaying items by tag: UWC
Deadline: 15 March 2023
Postdoctoral Fellowship 2023
Deadline: 23 February 2023
PhD Position SANBI
Deadline: 31 December 2022
Postdoctoral Fellowship (Laboratory)
Deadline: 15 April 2022
Bioinformatics Postdoctoral Fellowship
Deadline: 15 April 2022
Faculty of Natural Sciences, Institute for Microbial Biotechnology and Metagenomics IMBM
Technical Officer Position
Deadline: 28 November 2021
Postdoctoral Research Fellowship - University of the Western Cape
Deadline: 2 May 2021
Postdoctoral Research Fellowship / MSc in Biotech
Closing date: 9 Mar 2020 (Postdoc); 10 Mar 2020 (MSc)
The Nanobiotechnology Research Group in the Department of Biotechnology at the University of the Western Cape herewith invites potential students to enrol for an NRF-funded PhD or MSc degree to develop drug delivery systems for obesity. If interested, you may start either in the second semester of 2019 or the beginning of January 2020.
Obesity is a complex metabolic disease that poses serious public health problems worldwide. It is a risk factor for various life threatening chronic diseases such as type 2 diabetes, fatty liver disease, hypertension, dyslipidemia, atherosclerosis and osteoarthritis. Treatment of obesity using anti-obesity drugs, is limited by their non-specificity, and most of them have been withdrawn from the market due to severe adverse side effects. Therefore, there is an urgent need for the development of safe and effective drugs and treatment approaches in order to curb the obesity epidemic.
Our lab and others have shown that inhibiting angiogenesis by targeting a protein expressed on dysfunctional cells lining the blood vessels represents a promising strategy for obesity treatment. However, this strategy is limited by the use of only one targeting peptide. Thus, we want to discover other novel, specific and selective targeting agents to use for obesity treatment.
An in vivo model of obesity will be used to isolate potential targeting molecules. These agents will further be validated in cell culture for use as active targeting agents for obesity treatment. The selected agents will then be used to develop drug delivery systems for obesity treatment.
Studentships (MSc and PhD) with bursary funding for South African citizens are available. Experience in either cell biology, histology, biochemistry, microbiology, pharmacy or molecular biology (especially PCR) is required.