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uwcThe Institute for Microbial  Biotechnology and Metagenomics (IMBM) is a leading research unit based within the Department of Biotechnology at the University of the Western Cape (UWC). Our research employs culture-based approaches as well as cutting edge  ”omics”  strategies to study microbiomes and identify novel biosynthetic gene clusters and metabolites.  The Institute focuses on the research and development of novel,  high - value natural products for the pharmaceutical, cosmeceutical, food and beverage and agricultural industries, as well as products for industrial processes.


1. As part of 2 EU-funded consortia (PharmaSea and Ocean Medicines), this project focuses on marine bacteria shown to produce anti-convulsant, anti-cancer, anti-microbial or anti-inflammatory activities. Through genome sequencing and genetic engineering strategies in parallel with chemistry-guided isolation, we aim to: i) link novel metabolites to the biosynthetic pathways encoding them, and ii) develop over-expression strains for target pathways and compounds.

2. We are developing a portfolio of biosurfactants for use in a variety of industrial processes. The project involves the isolation and characterisation (chemical, structural and performance) of novel biosurfactants, as well as the upscaling of biosurfactant production.

Minimum Criteria:

Applicants must have completed a PhD degree within no more than 5 years in a foundational discipline relevant to the topic. Experience in natural product discovery and genomics is an advantage. Applicants should have a strong publication record, interpersonal skills, project management experience, and be able to effectively conduct research as part of a multi-disciplinary team.


Application Submission:

The candidate will be under the supervision of Prof. Marla Trindade who holds a DST/NRF Research Chair in Microbial Genomics. Applicants are to submit their CV and covering letter to This email address is being protected from spambots. You need JavaScript enabled to view it..


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